Fecha de recepción: 28/12/2016 – Fecha de aceptación: 30/11/2017
Mendoza-Aguilera M1, Ferrando-Piqueres R1, Álvarez Martín T1, Pascual Marmaneu O1, Liñana Granell C1,
Raga Jiménez C1, Minguez Gallego C2
1 Servicio de Farmacia
2 Servicio de Enfermedades Infecciosas
Hospital General Universitario de Castellón. Castellón de la Plana (España)
María Mendoza Aguilera
Hospital General Universitario de Castellón
Avda. Benicassim, s/n
12004 Castellón de la Plana
Correo electrónico: firstname.lastname@example.org
Objectives: The main objective of this study is to know the degree of adherence to antiretroviral treatment and the factors sociodemographic and related to treatment, that can influence it. As a secondary objective, the concordance between the two methods of adherence measurement is evaluated: SMAQ (Simplified Medication Adherence Questionnaire) and dispensing registration (RD) questionnaire.
Methods: A descriptive observational study assessing adherence to treatment in HIV-infected patients who receive their medication in a third-level hospital. Adherence is measured using the validated SMAQ questionnaire and the record of dispensations. Age, sex, family status, studies performed, occupation and other factors that could modify adherence such as the number of tablets, daily doses, duration of treatment, and adverse effects experienced with the current treatment were collected.
Results: The study evaluated a total of 60 patients infected with HIV. According to the SMAQ questionnaire, 45% of the patients are adherent; however, analyzing the registration of dispensations leads to an adhesion of 83.3%. 51.67% of the patients were classified in the same way by the SMAQ and RD method. No relationship was observed between the two measurement methods (p=0.304). No increased risk of virologic failure has been observed in non-adherent versus adherent patients. Regarding adherence to treatment, no statistically significant differences were found between the different sociodemographic factors, as well as those related to treatment and disease.
Conclusions: Recognizing the factors that affect adherence is an indispensable condition to improve patient care and obtain better health outcomes.
We should implement patient intervention programs, by experienced professionals, to improve health education and help them to increase or maintain adequate adherence.
Key Words: Adherence, antiretroviral treatment, HIV.