Rev. OFIL 2017, 27;3:264-271
Fecha de recepción: 01/07/2016 – Fecha de aceptación: 27/09/2016
Gallego Úbeda M1, Delgado Téllez de Cepeda L1, Campos Fernández de Sevilla MA1, Egües Lugea A1,
Iglesias Peinado I2, Tutau Gómez F1
1 Hospital Universitario del Henares. Coslada. Madrid (España)
2 Universidad Complutense de Madrid (España)
Marta Gallego Úbeda
Hospital del Henares
(Servicio de Farmacia)
Avda. Marie Curie, s/n
28822 Coslada (Madrid)
Correo electrónico: firstname.lastname@example.org
Background: The complexity of the use of drugs in patients with kidney disease requires developing methodologies for efficient care avoiding drug related problems (DRPs).
Objectives: To describe the characteristics of PI (pharmaceutical interventions) and their evolution over the studied period in patients with impaired renal function treated with drugs drugs that require adjustment.
Methods: retrospective study where a software (SONAR) based on interoperability (the ability to work integrated systems) was applied to three periods: P0: prior to implementing the tool; P1: at the beginning of the implementation, P2: one year after implantation.
A descriptive analysis was made for gender, age, MDRD-4, patients candidates for PI, patients with PI, number of PI, acceptance degree of PI, analysis distribution by drug and anatomic system.
Kruskal-Wallis test was applied to establish statistical significance .Statistically significant differences with a probability of less than 5% (p<0.05) was considerated.
Results: The number of PI is reduced from P1 (229) to P2 (96). The prescriber acceptance degree is increased (47.6% P1 vs. 77.1% P2). Drug with the highest number of PI: levofloxacin.
Most relevant PI had been at cardiovascular disease.
Conclusion: SONAR increases the detection efficiency of DRPs, shows a high degree of acceptance of the PI, generates learning effect and PI confidence in health professionals and PI, generates consensus and well documented recommendations, it is flexible and prevents the excess of alerts and can be easily implemented with multiple rules and criteria.
Key Words: Renal insufficiency, pharmaceutical intervention, interoperability, drug related problems, pharmaceutical validation, software.