Liñana Granell C, Montañés Pauls B, García Martínez T, Ibáñez Benages E
Hospital General Universitario de Castellón. Castellón de la Plana (España)
Rev. OFIL 2016, 26;3:171-174
Fecha de recepción: 30/10/2015 – Fecha de aceptación: 29/11/2015
Liver disorders and biliary system are common complications in patients receiving parenteral nutrition (PN) long term. Elevated gamma-GT, alkaline phosphatase and bilirubin are the most specific markers of liver disease associated with the PN. Strategies for the treatment of liver complications from parenteral nutrition are: adjust the caloric intake of the PN (carbohydrates and lipids), use of PN cyclic and early use of enteral nutrition. As part of our regarding prescription and preparation of the PN daily activity, it was observed that there was a group of patients with PN prolonged whose liver profiles within normal in the beginning, got worse during the period of artificial nutrition. The head of nutrition clinical pharmacist made a series of recommendations to reverse that failure in liver function. In this series of 8 cases it shows how, at the time that the cyclized nutrition starts, the hepatic disease associated with PN significantly begins to reverse. This is demonstrated by comparing pre- and post-liver cyclization analytical parameters.
Key Words: Total parenteral nutrition, liver disease, cyclic infusion.